"Türkmenistanyň lukmançylygy" žurnaly

Founder: Ministry of health and medical industry of Turkmenistan
Adress: Ashgabat c., Garashsyzlyk shayoly, 100, Turkmenbashy centre of free creative work
Telephones: 38-61-55
Email: t-lukmanchylygy-zurnaly@online.tm


Endocardial catheter ablation technique for atrial flutter

Atrial flutter (AF) is the most common type of supraventricular tachycardia, which is characterized by rhythmic frequent (200-350) atrial contractions per minute and delayed conduction of impulses in the ventricles due to macro – re-entry mechanism [4, 7]. Pathophysiological basis of AF is a decrease in the stroke volume of blood and a decrease in systemic and coronary blood flow, which contributes to myocardial dysfunction and dilatation of heart chambers, which is the cause of formation of intracardiac thrombi [2, 5]. The aim of the work is to study the effectiveness of treatment by endocardial catheter radiofrequency ablation in patients with paroxysmal atrial flutter.

Comprehensive use of diagnostic techniques of malignant gastric neoplasms

Currently, according to the frequency of morbidity and mortality, malignant neoplasms of stomach (MNS) take 2nd place [1, 4, 6, 7]. The main diagnostic method of MNS is esophagogastroduodenoscopy, which increased the detection of MNS at an early stage by 30%, allows morphological verification of the disease and planning treatment tactics [2, 5, 6]. MNS can be determined using ultrasound of abdominal organs. The early diagnosis of MNS today remains one of the urgent problems of practical oncology. The aim of the work is to analyze the possibilities of early diagnosis of malignant neoplasms of stomach with comprehensive use and develop a diagnostic algorithm.

Spectrophotometric determination of the pigment content in medicinal plants of Turkmenistan

The healing and physiological properties of medicinal plants are due to the presence in them of different groups of active substances, including pigments [1]. They are more often found in the leaves of medicinal plants (Fig. 1).

Diagnostics and treatment of hepatolenticular degeneration

Hepatolenticular degeneration (Wilson-Konovalov disease – WKD) is a hereditary disease, which is based on impaired copper metabolism, leading to its excessive accumulation in the liver, brain, cornea and other organs. According to modern research, WKD occurs much more often than previously thought: about 1:7000-10000 instead of 1:30000 [1]. Timely diagnosis and pathogenetic therapy can radically change the prognosis [5]. In the given clinical case, Wilson-Konovalov's disease with hepatocerebral dystrophy is described.

The use of two-phase nutrient medium for streptococcus pneumoniae isolation

Isolation and preservation for an indefinitely long term of microorganisms unstable in the external environment and demanding on nutrient media in bacteriological laboratories are associated with certain difficulties [3, 6, 7]. A representative of the Streptococcus genus S.pneumoniae also belongs to such microorganisms, the isolation of which is hampered not only by the mentioned difficulties, but also by S.pneumoniae's ability to autolysis [3, 6, 7]. Along with reliability of bacteriological diagnostic methods, cost-effectiveness is also important, availability of these methods, in accordance with this, population should be provided with high-quality and affordable health care services. Based on the foregoing, the preparation and use of biphasic nutrient media under laboratory conditions for cultivation and identification of S. pneumoniae is one of the urgent and priority issues of practical bacteriology.

Chronic background thyroid pathology as a factor of malignization of adenomas of thyroid gland

Over the past decades, an almost twofold increase in the frequency of thyroid cancer has been reported [13]. Analyzing the pathological processes against which thyroid cancer was detected, the researchers note that only in 22,8% of cases this background was absent, and in the remaining 77,1%, the background for development of thyroid cancer were adenomas, chronic autoimmune thyroiditis (AIT) and nodular goiter (NG) [7, 9]. It remains unclear which particular processes can play a decisive role in their malignancy in this case, since previous works had morphologically descriptive character. Of them, which implied a quantitative assessment of the criteria of benign and malignancy, did not include changes in the stroma of the adenomas and gland tissue around them [8]. The aim of the work is to characterize the pathomorphological changes in thyroid gland with autoimmune thyroiditis and nodular goiter from a histomorphometric point of view and evaluate their role in the process of malignization of adenomas.

The role of family doctors in the fight against breast cancer

Family doctors conduct public health education aimed at the prevention and treatment of diseases, which is very important in relation to the prevention, early detection and treatment of malignant tumors and precancerous diseases, including breast cancer (BC) [2, 6, 12, 15]. The study of the work carried out by family doctors against malignant tumors, including against breast cancer, is an urgent, significant task of modern oncology, and for this, guidelines should be developed to improve this work.

The role of health schools in prevention of coronary heart disease

The importance of CHD problem lies in the prevalence, prolonged and severe clinical course, as well as in the high frequency of mortality and disability [5]. The study of the quality of life of patients with coronary heart disease does not lose its relevance. At present, it can be considered proven that lifestyle change and the fight against risk factors before the onset of clinical signs of a disease and after helps to slow the development of CHD.

Clinicofunctional indicators of chronic catarrhal gingivitis in children

Mixed saliva in children is an important biotope of oral cavity, with its help, the connection is preserved with other parts of microbiocenosis and various regulatory mechanisms are implemented by the macroorganism [1-3, 5, 9, 13]. In periodontal inflammation, the biochemical, cytological, microbiological, crystallographic composition and amount of emitted biological fluid is disturbed [6, 7, 14].

Pharmacoepidemiology of the use of antihypertensive drugs by family doctors

Arterial hypertension (AH) is a noncommunicable disease that is widespread among the population and a major risk factor for cardiovascular complications, requires longterm checkup, and in many cases, continuous treatment in polyclinics. Therefore, conducting largescale pharmacoepidemiological studies to analyze the features of the use of antihypertensive drugs by family doctors is of great importance for health care system of our country [14, 6]. The aim of the work is to study the peculiarities of prescription of antihypertensive drugs in polyclinics and analyze their compliance with current international recommendations.

Examining the predisposition of young children to anemia

Chary NAZAROV, Hojanepes ANNANEPESOV, Atageldy DJUNELOV, GUL GARRYYEVA,Scientific Research Center, Department of Pharmacology of M.Garryyev SMUT, International Educational and Scientific Center Anemia and micronutrient deficiency directly affect the health of children and mothers. For this reason, incidence rate increases, a lag in physical and neuropsychic development arises, which affects the formation of mental abilities and functional activity [5, 7, 10-12].

Medical and ecological aspects of antibiotic resistance

Annamyrat ALLABERDIYEV, Tylla TANRYBERDIYEVA, Jahan MEZILOVA, Mahri BEKNEPESOVA,Department of Hospital Therapy with a Course of Clinical Pharmacology and Endocrinology of M.Garryyev SMUT According to the World Health Organization (WHO), antibiotic resistance is currently one of the greatest danger to global health [1].