"Türkmenistanyň lukmançylygy" žurnaly

Founder: Ministry of health and medical industry of Turkmenistan
Adress: Ashgabat c., Garashsyzlyk shayoly, 100, Turkmenbashy centre of free creative work
Telephones: 38-61-55
Email: t-lukmanchylygy-zurnaly@online.tm


Fortification of wheat flour with iron on flour mills of Turkmenistan

Fortification of staple foods such as wheat flour, salt and oil makes these foods more nutritious and does not require changing eating habits. The most typical components of a premix to be added to flour are iron salts and folic acid [5].

Humoral immunity state of the population against COVID-19 infection

Despite the economic downturn in the developed countries of the world during COVID-19 pandemic, owing to the "Open Door" policy announced by the esteemed President of Turkmenistan Gurbanguly Berdimuhamedov, international relations in our country are developing rapidly. Based on decisions taken by the Emergency Commission of Turkmenistan for combating the spread of disease in order to protect the borders of Turkmenistan from the pandemic infection COVID-19 and to prevent the spread of this infection across the country, the epidemiological well-being is under strict control.

Results of treatment of HER 2-positive breast cancer

The incidence of malignant mammary tumors (MMT) is one of the first among oncological diseases in the world and in Turkmenistan. According to the WHO data, 1 million 700 thousand women fall ill annually in the world [1]. Immunohistochemical (IHC) and other molecular genetic studies are of great importance in determining the biological characteristics of MMT [2-4].

Comorbidities of coronary heart disease in Turkmenistan

According to the WHO, in 2018, 17,9 million people die annually from cardiovascular disease (CVD), and this is 31% of all deaths in the world [8]. Most of the patients seeking medical help for CVD, and in particular coronary heart disease (CHD), have several diseases of the internal organs. Comorbidity in CHD in Turkmenistan has not yet been studied enough. In this regard, the study of factors that can affect the course of CHD continues to be an important task of fundamental and clinical cardiology. The aim of the work is to study the presence of comorbid conditions and the structure of comorbidity in patients with stable angina pectoris in Turkmenistan.

Optical coherence tomography for the diagnosis of age-related macular degeneration

Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision loss. This pathology is bilateral and leads to primary disability in people over 50 years old. According to various sources, central vision impairment due to AMD was observed in 10% of people aged 65-75 years, and in people over 75 years old in 30% [2, 3]. Genetic factors and the environment play an important role in the development of AMD. Risk factors include hypertension, atherosclerosis, smoking [1, 3, 4]. The aim of the study is to determine the effectiveness of optical coherence tomography for the diagnosis of AMD.

Peculiarities of the development of reproductive function in adolescent girls with hypothyroidism

At present, hypothyroidism occupies a leading place in the structure of the general endocrine pathology of adolescent girls. Disorders associated with hypothyroidism can lead to changes in the menstrual cycle, infertility, miscarriage [8, 12].

Surgical treatment of benign liver tumor in infants

Benign liver tumors are the most common diseases in childhood, however, due to the absence of clinical symptoms, they are discovered by chance, when examining another pathology of the patient [1, 3, 7]. We present a clinical case of surgical treatment of a 16-day-old newborn with liver tumor.

Influence of seasonality on lipid peroxidation processes in pregnant women

Lipid peroxidation (LPO) reactions are a natural link of various metabolic processes. LPO activation is one of the important pathogenetic mechanisms of the onset and development of free radical pathology. In addition, highly sensitive LPO processes are actively involved in the body's responses to the action of various environmental factors [6, 7]. The intensity of LPO processes was judged by the content of its final product, malondialdehyde (MDA) [8].

Studying the possibilities of combined application of digital and traditional technologies in orthopedic dentistry

CAD/CAM – a modern technology for the production of dentures using computer-aided design and automated manufacturing on machine tools is one of the most promising areas in prosthetic dentistry. By using CAD/CAM technology, it is possible to produce various dental prostheses of the highest precision, excellent biocompatibility and flawless aesthetics with high work automation. Using CAD/CAM systems, it is possible to create single crowns, short and long bridges, telescopic crowns, individual abutments for implants, recreate the full anatomical shape for press-ceramic models, create temporary crowns, sprig teeth, inlays and veneers. The material can be zirconium dioxide, titanium, ceramics, cobalt-chromium alloy, plastic, wax.

Innovative digital technologies for ophthalmic screening and monitoring of premature infants

Pathology of the vision organ in premature infants (PI) is one of the leading problems in pediatric ophthalmology. The most severe diseases are retinopathy of prematurity (ROP), partial atrophy of the optic nerve, glaucoma, congenital myopia, developmental anomalies leading to blindness [1, 2]. For newborns weighing less than 2500 g, the introduction of a systematic approach to early detection of retinal pathology, conducting methods of careful ophthalmological monitoring to prevent irreversible changes are of medical and social importance [3]. This is due to the specificity of its clinical manifestations, early onset (the first weeks of a premature baby's life) and rapid course [7].

Effectiveness of complex anti-inflammatory treatment with the application of Mollagara mud for tuboperitoneal infertility

Tuboperitoneal infertility occurs in 20-30% of cases of female infertility and often occurs in chronic inflammatory processes of the genitals [6, 7]. In addition, the reasons may be surgical interventions which were performed on the pelvic organs, uterine cavity, as well as adhesions of the pelvic organs [8]. Because of several reasons, some patients need to use only conservative methods of treatment, which in turn require to be improved.

Peculiarities of myocardial revascularization in patients with myocardial ischemia in combination with arterial hypertension

Arterial hypertension (AH) is the main cause of risk associated with atherosclerosis. On the one hand, AH promotes the growth of atherosclerotic lesions of the coronary vessels, on the other hand, as a result of an increase in blood pressure (BP), functional and structural disorders of coronary blood supply and vascular remodeling of heart increase [3-5].

Methodological aspects of organization of Health schools

Human health is 50% determined by the way of life, that is, by his behavior and attitude to his own health and the health of others; one of the priority areas of activity in health protection is the formation of healthy lifestyle skills in people, and an increase in the level of sanitary and hygienic culture. Well-planned and organized activities to promote a healthy lifestyle among the population in health schools contribute to a decrease in morbidity and mortality, since chronic non-communicable diseases have common risk factors of a behavioral nature, approaches to their prevention are not resource-intensive, but can give a tangible socio-economic effect.

Modern diagnostics and treatment of psoriatic arthritis

Psoriatic arthritis (PA) is a chronic disease characterized by damage to the skin and joints [4, 13, 26]. PA belongs to the group of seronegative spondyloarthritis. PA develops in about 10-30% of people, more often at the age of 30-50 years [6, 18]. The cause of PA is not fully understood. Along with the immune system, genetic factors play a certain role in the development of the disease [7, 14].

Closed chest injury complicated by traumatic asphyxia

Diagnostics and treatment of closed chest injuries are the urgent problems of thoracic surgery and traumatology [1, 3-5]. Traumatic asphyxia is a complication that occurs with strong and short-term compression of a chest or an abdomen. A diagnosis of traumatic asphyxia is established on the basis of complaints, anamnesis, the mechanism of a trauma, clinical picture and instrumental studies [2, 5, 7, 8]. We present a rare occurence of traumatic asphyxia as a result of closed chest injury with compression.

Diagnostics and treatment of mediastinal tumors

Due to the morphological diversity of mediastinal tumors, their clinical course and treatment results differ from each other. Due to the variety of morphological structures of mediastinal tumors, the clinical parameters of disease are different and have their own peculiarities of the course [4, 5].

Organ-preserving operations for placenta previa and placenta accreta

Despite the development of science in general, and in particular the development of obstetrics, at present, maternal mortality remains one of the primary problems in different countries [1, 2]. In our country and abroad, numerous scientific works are devoted to the problem of maternal mortality, the main focus of which is the study of causes, prevention and conducting quality treatment, which allows to avoid irreversible consequences of obstetric bleeding. For a long time, there was a provision on the need for a planned hysterectomy for placenta previa and placenta accreta in order to avoid massive bleeding [3, 5]. According to the literature and on the recommendations of foreign authors, in case of pathology of the placenta, methods of organ-preserving operations are used [4]. The aim of the work is to analyze the results of managing patients with placenta previa and true placenta accreta.

Changes in portal hemodynamics in patients with liver cirrhosis

Latent course of many chronic diffuse liver diseases and, as a result, their delayed diagnosis underlie the frequent formation of liver cirrhosis (LC) [7, 9]. The cause of death of patients with LC is mainly complications of portal hypertension (PH), among which bleeding from esophageal varicose veins dilatation (EVVD) is 40%, hepatic encephalopathy 30%, infectious (pneumonia, spontaneous bacterial peritonitis, urinary infections) complications 30%. Changes in intrahepatic hemodynamics play one of the key roles in the pathogenesis of hepatic diseases. Doppler ultrasound of vessels of the portal system is considered an affordable, informative and non-invasive method in the early diagnosis of liver diseases [8].

Modern aspects of myopia diagnosis in children

Myopia is distinguished by a variety of clinical forms, complexity of pathogenesis, which includes biomechanical, vascular and metabolic factors, difficulty of early diagnosis and treatment, severity of prognosis and the high medical and social significance of disease [1-3]. The use of optical coherence tomography (OCT) for the first time makes it possible for a high-precision objective qualitative and quantitative assessment of reticular and vascular tunic of eye, which opens up wide opportunities in graft morphometric study of various segments of the fundus of eye in myopia [4]. The aim of the work is to identify morphometric diagnostic signs of myopia progression by means of optical coherence tomography of the fundus of eye in children.

The effect of ecological crisis of the Aral sea on the health state of the population

Ecological crisis of the Aral Sea affects 60 million population of Central Asia and an area of about 25 million hectares [2, 10]. The Aral Sea is a saltwater lake or inland sea in Central Asia. Overconsumption of water for irrigating agricultural land has turned the fourth largest sea-lake in the world, previously rich in life, into a barren desert [6]. Shrinking Aral Sea is one of the most powerful sources of natural aerosols entering the atmosphere [2].